IV Ketamine Therapy

For some individuals living with treatment-resistant depression, traditional treatments may not provide adequate relief. IV ketamine therapy is an evidence-based treatment option that may be appropriate for certain patients following a comprehensive psychiatric evaluation. Our providers carefully assess each patient's medical and psychiatric history to determine whether IV ketamine therapy is an appropriate part of an individualized treatment plan.

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What Is IV Ketamine Therapy?

IV ketamine therapy involves the administration of a carefully controlled, low-dose ketamine infusion in a comfortable clinical setting under the supervision of trained healthcare professionals. Unlike traditional antidepressants, ketamine works through the brain's glutamate system, offering a different treatment approach for certain individuals with treatment-resistant depression. Every infusion is administered with continuous monitoring to help ensure your safety and comfort throughout treatment.

IV ketamine has been extensively studied as a treatment option for individuals with treatment-resistant depression who have not experienced adequate improvement with conventional therapies.

Evidence-Based Treatment

Every patient begins with a comprehensive psychiatric evaluation. Treatment recommendations are based on your diagnosis, medical history, previous treatment response, and overall clinical needs to help determine whether IV ketamine therapy is appropriate.

Individualized Care

Each infusion is administered in a comfortable clinical setting with continuous monitoring by trained healthcare professionals. Your safety, comfort, and overall treatment experience remain our highest priorities throughout every visit.

Carefully Monitored

Who May Benefit from IV Ketamine Therapy?

IV ketamine therapy is not appropriate for everyone experiencing depression. Every patient undergoes a comprehensive psychiatric evaluation to confirm the diagnosis, review previous treatments, and determine whether IV ketamine therapy may be an appropriate part of an individualized treatment plan.

IV ketamine therapy may be appropriate for adults with treatment-resistant depression who have not experienced adequate improvement despite appropriate trials of traditional antidepressant medications.

Treatment-Resistant Depression

Previous Medication Challenges

Not everyone with depression is a candidate for IV ketamine therapy. A thorough psychiatric evaluation helps ensure that treatment recommendations are safe, appropriate, and tailored to your individual needs, medical history, and treatment goals.

Comprehensive Evaluation Required

What to Expect During Treatment

Every patient begins with a comprehensive psychiatric evaluation before IV ketamine therapy is recommended. If treatment is appropriate, our team will guide you through each stage of care—from your initial consultation and induction series through ongoing progress assessments and maintenance treatment when clinically indicated.

Step 1

Before beginning IV ketamine therapy, you'll meet with one of our psychiatric providers for a comprehensive evaluation. We'll review your symptoms, treatment history, medical history, current medications, and treatment goals to determine whether IV ketamine therapy is an appropriate treatment option.

Comprehensive Psychiatric Evaluation

Step 2

If IV ketamine therapy is recommended, we'll develop an individualized treatment plan based on your diagnosis, symptom severity, previous treatment response, and overall clinical needs. We'll also review the treatment process, answer your questions, and discuss what to expect before your first infusion.

Individualized Treatment Planning

Step 3

Most patients begin with an induction series consisting of six IV ketamine infusions administered over approximately two to three weeks. This structured treatment schedule is designed to provide the best opportunity for response while allowing your provider to monitor your progress throughout therapy.

Induction Series

Step 4

Each treatment is administered in a comfortable clinical setting over approximately 40 minutes. Throughout your infusion, our clinical team continuously monitors your vital signs, comfort, and overall treatment experience to help ensure your safety.

Infusion Appointments

Step 5

Throughout treatment, your provider will regularly assess your symptoms using validated clinical rating scales, review your response to therapy, and discuss any changes in your symptoms or treatment goals. These assessments help guide individualized treatment recommendations throughout your course of care.

Ongoing Progress Monitoring

Step 6

Following completion of the induction series, some patients benefit from maintenance or booster infusions based on symptom recurrence, treatment response, and clinical judgment. Your provider will discuss whether additional treatments may be appropriate as part of your long-term treatment plan.

Booster Treatments

Why an Induction Series?

IV ketamine therapy is typically delivered as a series of treatments rather than a single infusion. This approach allows your provider to evaluate your response over time and helps establish an individualized treatment plan based on your symptoms and clinical progress. Throughout the induction series, your treatment team closely monitors your response and discusses recommendations for ongoing care.

Preparing for Your Treatment

Preparing for your IV ketamine infusion is simple. Our team will provide detailed instructions before your first appointment and answer any questions you may have. Following these recommendations helps ensure your treatment is as safe and comfortable as possible.

Take your medications as directed unless instructed otherwise by your provider.
Avoid eating for at least two hours before your infusion.
You may drink clear liquids until 30 minutes before your appointment.
Wear comfortable clothing.
Arrange for a responsible adult to drive you home following treatment.

Before Your Appointment

Your infusion will be administered over approximately 40 minutes in a comfortable treatment room.
Your blood pressure, heart rate, and overall condition will be monitored throughout your treatment.
Many patients experience temporary changes in perception, relaxation, or dissociation during the infusion.
Your treatment team will remain available throughout your visit to ensure your comfort and safety.

During Your Infusion

You'll remain in the office until your provider determines you are ready for discharge.
You must have a responsible adult drive you home following every infusion.
Do not drive, operate heavy machinery, or make important decisions until the following day after a restful night's sleep.
Plan for a quiet remainder of the day and follow any discharge instructions provided by your treatment team.

After Your Treatment

Every patient's experience is unique. Our team will discuss what you may experience during treatment and answer any questions before your first infusion begins.

Safety & Monitoring

Patient safety is our highest priority throughout every stage of IV ketamine therapy. Before treatment begins, every patient undergoes a comprehensive psychiatric evaluation and medical screening to help determine whether IV ketamine therapy is appropriate. During each infusion, our clinical team continuously monitors your condition to help ensure treatment is delivered safely and comfortably.

Before recommending IV ketamine therapy, we carefully review your psychiatric history, medical history, current medications, and previous treatment response. This evaluation helps determine whether IV ketamine is an appropriate treatment option and allows us to develop an individualized treatment plan.

Comprehensive Medical Evaluation

Throughout every infusion, our clinical team continuously monitors your blood pressure, heart rate, oxygen saturation, and overall comfort. Your provider remains available throughout treatment, and your recovery is assessed before you're discharged home.

Continuous Monitoring

Treatment doesn't end when your infusion is complete. We regularly assess your symptoms, review your response to treatment, monitor for side effects, and adjust your treatment plan when clinically appropriate to help support your long-term progress.

Individualized Follow-Up

Our goal is to provide safe, evidence-based care while ensuring every patient feels informed, comfortable, and supported throughout their treatment journey.

Treatment Costs & Payment

We believe patients should have a clear understanding of treatment costs before beginning care. IV ketamine therapy is offered as a self-pay service at our practice because most commercial insurance plans, Medicare, and Ohio Medicaid do not provide coverage for IV ketamine infusions used for psychiatric conditions.

Most patients begin with a series of six IV ketamine infusions completed over approximately two to three weeks.

Six infusions: $1,350

This averages $225 per infusion.

Includes comprehensive psychiatric evaluation, individualized treatment planning, approximately 40-minute monitored infusions, continuous vital sign monitoring, and ongoing symptom assessments throughout your treatment course.

Induction Series

Following the induction series, some patients benefit from maintenance or booster infusions based on symptom recurrence, treatment response, and clinical judgment. Your provider will discuss an individualized maintenance schedule and the cost of additional treatments with you before they are scheduled.

Maintenance Treatments

Your treatment plan, payment expectations, and applicable policies will be reviewed before treatment begins. We openly share our pricing so you can make an informed decision without hidden charges or unexpected treatment fees.

Clear, Upfront Pricing

Intravenous ketamine is not currently FDA-approved for the treatment of depression, which is why insurance plans generally do not cover it for psychiatric use. During your evaluation, your provider will also discuss other clinically appropriate options, including insurance-covered treatments such as Spravato® or TMS when applicable.

Frequently Asked Questions

IV ketamine therapy involves the administration of a carefully controlled, low-dose ketamine infusion under the supervision of trained healthcare professionals. Ketamine works differently than traditional antidepressants and may be an appropriate treatment option for certain individuals with treatment-resistant depression following a comprehensive psychiatric evaluation.
Every patient begins with a comprehensive psychiatric evaluation. During this appointment, your provider will review your symptoms, previous treatments, medical history, current medications, and treatment goals to determine whether IV ketamine therapy is an appropriate option.
Although both treatments are derived from ketamine and may be used for treatment-resistant depression, they are administered differently and have different regulatory requirements. Spravato® is an FDA-approved intranasal medication available only through a REMS-certified program, while IV ketamine is administered by intravenous infusion. During your evaluation, your provider will discuss which treatment, if any, is most appropriate for your individual needs.
IV ketamine therapy is typically delivered as a series of treatments rather than a single infusion. An induction series allows your provider to monitor your response over time, assess symptom improvement, and develop an individualized long-term treatment plan based on your clinical progress.
The ketamine infusion itself is administered over approximately 40 minutes. Including preparation, monitoring, and recovery, you should plan to be in the office for approximately 90 to 120 minutes for each appointment.
Yes. Patients remain awake throughout treatment. Many individuals experience temporary changes in perception, relaxation, or dissociation during the infusion, but our clinical team remains with you and continuously monitors your treatment throughout the visit.
No. Because ketamine can temporarily affect judgment, coordination, and reaction time, you must arrange for a responsible adult to drive you home following every infusion. Do not drive, operate heavy machinery, or make important decisions until the following day after a restful night's sleep.
Every patient's response is different. Some individuals notice changes early in treatment, while others experience more gradual improvement throughout the induction series. Your provider will regularly assess your progress and discuss your response throughout treatment.
Common side effects may include temporary dissociation, dizziness, nausea, blurred vision, elevated blood pressure, or changes in perception during treatment. These effects typically resolve before you leave the office, and our clinical team continuously monitors you throughout every infusion.
Most commercial insurance plans, Medicare, and Ohio Medicaid do not currently cover IV ketamine infusions for the treatment of depression. Because of this, IV ketamine therapy is offered as a self-pay service at our practice.
We believe financial considerations should not be an unnecessary barrier to evidence-based mental health care. Our practice is intentionally designed to provide high-quality psychiatric care in an efficient outpatient setting while maintaining the same commitment to patient safety, individualized treatment planning, continuous clinical monitoring, and ongoing psychiatric follow-up. Our focus is delivering exceptional clinical care at a transparent and competitive price.
Treatment-resistant depression is often a chronic condition, and every patient's course is different. While some individuals experience sustained improvement after completing the induction series, others may benefit from maintenance infusions based on symptom recurrence and clinical response. Your provider will work with you to develop an individualized long-term treatment plan and determine whether maintenance therapy is appropriate.
IV ketamine therapy is not appropriate for everyone. Certain medical and psychiatric conditions may make treatment inappropriate or require additional evaluation before therapy begins. During your comprehensive psychiatric evaluation, your provider will review your medical history, current medications, and overall health to determine whether IV ketamine therapy is a safe and appropriate treatment option.
The first step is to request a comprehensive psychiatric evaluation. During this appointment, your provider will review your symptoms, treatment history, medical history, and treatment goals to determine whether IV ketamine therapy is appropriate. If recommended, our team will guide you through every step of treatment, from your induction series to ongoing follow-up and maintenance planning.

If you've been living with treatment-resistant depression despite trying traditional treatments, you don't have to navigate the next steps alone. Our team provides comprehensive psychiatric evaluations to determine whether IV ketamine therapy—or another evidence-based treatment—is appropriate for your individual needs. We'll take the time to understand your history, answer your questions, and develop a personalized treatment plan focused on helping you achieve meaningful, lasting improvement.

Ready to Learn Whether IV Ketamine Therapy Is Right for You?